Study Proves Insulin Like Growth Factor-1 Can Repair Nerve Damage

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Study Proves Insulin Like Growth Factor-1 Can Repair Nerve Damage

This latest Study showing Insulin Like Growth factors ability to repair nerve damage backs up what many in the fitness and bodybuilding community have been saying for almost 2 decades!

The reason I myself am such a proponent of IGF 1 Lr3 is due to my being introduced to it after doctors told me my left quad had nerve damage to such a degree that it would never fire again (flex) .

This nerve damage came 1 month from my last bodybuilding show, and a year of atrophy had seriously set in to my left quad. It was then I had started to inject the Long R3 IGF-1 I had purchased direct from Gropep back in 2002 or 2003. Within a month My quad was flexing , firing, contracting on all cylinders! Although the atrophy was so severe it took a year to get my quads developed equally again! So yes IGf 1 lr3 does indeed repair damaged nerves! It did for me!

Researchers at the University of Illinois at Chicago College of Medicine have found that a growth factor can regenerate damaged peripheral nerves without causing the growth of new blood vessels — making it a unique candidate to treat nerve damage in areas of the body where the proliferation of blood vessels would be a drawback.

“One example would be in the cornea, which has a requirement for dense innervation but where the formation of new blood vessels would block vision,” said Dr. Mark Rosenblatt, professor and head of ophthalmology and visual sciences at UIC and corresponding author on the study, published in the Proceedings of the National Academy of Sciences.

Peripheral nerves — those outside the brain, spinal cord and optic nerve — have the capacity to regenerate when damaged. The process is guided by numerous signaling mechanisms, including a family of growth factors called VEGFs, or vascular endothelial growth factors, which are involved in the development of blood vessels as well as nerves. Understanding exactly how they work could lead to the development of drugs that enhance the body’s ability to repair damaged nerves.

VEGF-A is a factor that Rosenblatt and several others have studied extensively. It helps repair damaged nerves, but also induces angiogenesis – the formation of new blood vessels. Rosenblatt and colleagues wanted to better understand the role of a related growth factor, VEGF-B, in neuroregeneration and angiogenesis. They investigated its effects in the corneas of mice.

They found that mice lacking VEGF-B had a significantly impaired ability to repair damage to the corneal nerve. But if VEGF-B was delivered to the corneas of these mice, nerve regeneration improved. The new nerves restored normal sensation to the eye, and proper secretion of chemical signals to maintain the health of the cornea.

Importantly, the researchers also found that treatment with VEGF-B did not induce formation of new blood vessels, or have any effect on undamaged nerves.

In experiments with normal mice able to produce VEGF-B, Rosenblatt saw that levels of the growth factor rose significantly around corneal nerves after they were damaged.

“The selective effects of VEGF-B on injured nerves — and its lack of angiogenic activity — suggest that its main function may be neuroregeneration,” Rosenblatt said.

The findings, he said, warrant further investigation of VEGF-B as a potential therapy to treat corneal nerve damage, which can be caused by dry eye, contact lenses, viruses or eye surgery, in addition to trauma. As a treatment, VEGF-B may prove superior to nerve growth factor, which has been used to treat certain eye diseases but can cause significant eye pain or the growth of new blood vessels.

 

Immense Growth Factor Benefits For Elite Athletes Using IGF 1 lr3

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